Marguarite De La Motte was born on June 22, 1902 in Duluth, Minnesota. She studied Ballet under the Anna Pavlova and was soon a feature attraction at Sid Grauman's theatre. Her parents killed in a car crash, Producer J.L. Frothingham became her guardian at about the time of her debut as a movie actress in 1918.

A stunning looking actress, Marguarite De La Motte was popular during the silent movie era, but did not adapt well to sound. She continued to work in minor, less frequent, roles.

Marguarite De La Motte was married to, and divorced from, movie actor John Bowers. Sadly, Marguarite De La Motte passed away from cerebral thrombosis on March 10, 1950. She was only 48 years old.

A prolific actress during the silent movie era, some of her films include:

• Arizona (1918)
• For a Woman's Honor (1919)
• The Pagan God (1919)
• The Broken Gate (1920)
• The U.P. Trail (1920)
• The Mark of Zorro (1920)
• Fools of Fortune (1922)
• The Three Musketeers (1921)
• Wandering Daughters (1923)
• A Man of Action (1923)
• Fifth Avenue (1926)
• Hearts and Fists (1926)
• A Woman's Man (1934)
• Overland Mail (1942)